parsisotope
Order registration
| Contact Us |

Follow Us:

LinkedIn
Instagram
Telegram
YouTube
mail

info@Parsisotope.com

phone

+98-2142180000

location_on

No.88, West 23rd St.Azadegan Blvd. South Sheykh Bahaie Ave. Tehran, Iran

language
PersianSpanishArabic

PARS‑BOMBESIN® Kit

 Sterile, NonPyrogen Lyophilized Powder

done
SPECT Imaging
done
Diagnostic
circle
About the Product

PARS‑Bombesin is a sterile, non‑pyrogen lyophilized radiopharmaceutical kit for the preparation of the diagnostic radiopharmaceutical 99mTc‑Hynic Bombesin. After radiolabeling with technetium‑99m, it is used for SPECT imaging of tumors expressing the GRPR (gastrin‑releasing peptide) receptor. Each vial contains 25 µg of Hynic GABA Bombesin peptide and, after reconstitution, is administered intravenously. This radiopharmaceutical is intended solely for diagnostic use.

circle
Applications
  • Diagnosis and imaging of GRPR‑expressing tumors, such as certain prostate, breast, gastrointestinal, and neuroendocrine cancers
  • Assessment of tumor location, extent, and possible metastases
  • Evaluation of GRPR expression to aid in the selection of targeted therapeutic approaches
circle
Mechanism of Action

After intravenous administration, 99mTc‑Hynic Bombesin distributes in the bloodstream and binds to GRPR receptors on the surface of certain tumor cells. As a result, the radiopharmaceutical accumulates in these areas, and technetium‑99m, through gamma emission, enables detection and imaging of these regions using a gamma camera.

circle
Preparation and Administration

Note: This pharmaceutical product is intended solely for use in nuclear medicine facilities by personnel experienced in handling radiopharmaceuticals.

The PARS‑Bombesin®️ kit is manufactured under aseptic conditions. After radiolabeling with a specified amount of sterile, non‑pyrogen sodium pertechnetate injection (Na99mTcO₄) — eluted from a 99Mo/99mTc generator — the preparation is ready for intravenous administration. The dose to be used will be prescribed by the physician.

circle
Box Contents

Each box contains one instruction leaflet, one Bombesin kit vial, and one label specifically for the radiolabeling procedure.

circle
Composition

Hynic‑GABA Bombesin (25 µg)

Stannous Chloride Dihydrate

Mannitol

Tricine

EDDA

circle
Storage Conditions
  • The PARS‑Bombesin®️ kit should not be used after the expiration date printed on the box.
  • Store the PARS‑Bombesin®️ kit in a freezer (-8°C to -20°C) and protected from light. The cold chain must be maintained under all circumstances.
  • After radiolabeling, 99mTc‑Hynic Bombesin must be used within 4 hours and stored at 15°C to 25°C.
You must be logged in to post a comment.
Menu