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PARS‑RBC(sn++)® Kit

 Sterile, NonPyrogen Lyophilized Powder

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SPECT Imaging
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Diagnostic
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About the Product

PARS‑RBC (Tin++) is a sterile, non‑pyrogen lyophilized radiopharmaceutical kit for blood pool and vascular space imaging. After radiolabeling of red blood cells followed by labeling with Tc‑99m, it is used for SPECT imaging. The RBC kit is intended solely for diagnostic use and for the preparation of 99mTc‑RBC.

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Applications
  • Diagnosis of internal bleeding
  • Diagnosis of active gastrointestinal bleeding (GI Bleeding scan)
  • Diagnosis of hepatic hemangioma
  • Evaluation of vascular anomalies and shunts
  • Assessment of splenic trauma or blood pooling
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Mechanism of Action

After the RBC kit is radiolabeled with the patient’s blood sample and then with technetium‑99m under aseptic conditions, it is reinjected intravenously. 99MTc‑RBC then enters the bloodstream and remains mainly within the vessels. In areas with active bleeding or vascular lesions, the radiolabeled red blood cells leak out of the vessels and accumulate, allowing the bleeding sites to be imaged using a gamma camera.

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Preparation and Administration

Note: This pharmaceutical product is intended solely for use in nuclear medicine facilities by personnel experienced in handling radiopharmaceuticals.

The PARS‑RBC (Tin++)®️ kit is manufactured under aseptic conditions. After a multi‑step radiolabeling process with a specified amount of red blood cells from the patient’s blood sample and sterile, non‑pyrogen sodium pertechnetate injection (Na99MTcO₄) — eluted from a ⁹⁹Mo/99MTc generator — the preparation is ready for intravenous administration. The dose to be used will be prescribed by the physician.

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Box Contents

Each box contains one instruction leaflet and three vials (kit vial, buffer solution vial, and ACD solution vial), along with one label specifically for the radiolabeling procedure.

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Composition

Stannous Chloride Dihydrate (105 µg)

Sodium Citrate Dihydrate

Anhydrous Dextrose

Sodium Hypochlorite Buffer Solution

ACD Solution

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Storage Conditions
  • Store the PARS‑RBC (Tin++)®️ kit in a refrigerator (2°C to 8°C) and protected from light. The cold chain must be maintained under all circumstances.
  • After radiolabeling, 99MTc‑RBC remains stable for a maximum of 30 minutes at 15°C to 25°C.
  • The PARS‑RBC (Tin++)®️ kit should not be used after the expiration date.
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